Recent Updates in CAR-T Cell Therapy and Their Impact in Clinical Practice in RRMM

Author(s):

Panelists discuss how ciltacabtagene autoleucel (cilta-cel) demonstrates superior outcomes compared to real-world physician’s choice of therapy in patients with late-line relapsed/refractory multiple myeloma (RRMM), with significantly higher response rates, deeper remissions, longer progression-free survival and potentially improved overall survival, though they acknowledge the challenges of cross-trial comparisons and emphasize the importance of considering patient-specific factors such as fitness, prior therapy exposure and treatment goals when weighing this one-time cellular therapy against sequential conventional approaches.

Cilta-cel vs real-world physician’s choice of therapy

Recent Updates in CAR-T Cell Therapy and Their Impact in Clinical Practice in RRMM

EP: 1.What is Late-Line RRMM and How is it Determined?

EP: 2.Challenges in Managing Late-Line RRMM

EP: 3.Linda’s Treatment History and Challenges in Coping With Multiple Relapses

EP: 4.Current Treatment Landscape for Late-Line RRMM

EP: 5.Clinical Factors Evaluated When Choosing Treatment in Late-Line RRMM

EP: 6.Patient’s Experience in Shared Decision Making in RRMM

EP: 7.Practical Considerations for Therapies Considered by the Patient and Caregivers in RRMM

EP: 8.Managing Treatment Logistics: Navigating Travel, Lodging and Caregiver Support

EP: 9.Recent Updates in Bispecifics and Their Use in Clinical Practice

EP: 10.Recent Updates in CAR-T Cell Therapy and Their Impact in Clinical Practice in RRMM

EP: 11.Balancing Benefits and Risks: Patients’ Experiences With Newer Therapies and Side Effects in Late-Line RRMM

EP: 12.Balancing Efficacy and Quality of Life in Late-Line RRMM

EP: 13.Aligning Treatment Goals: Key Considerations for Patients and Caregivers in Late-Line RRMM

EP: 14.Lifestyle Modifications That Have Been Helpful in RRMM

EP: 15.Addressing the Most Common Concerns Patients and Caregivers Have in Late-Line RRMM

EP: 16.Effective Communication Strategies: Sharing Concerns With Your Medical Team in Late-Line RRMM

EP: 17.Guidance for Caregivers: Supporting a Loved One Through Late-Line RRMM

EP: 18.Navigating RRMM: Helpful Resources and Advice for Patients Facing Disease Progression