MPN

Second-line treatment with Inrebic has been shown to be beneficial for patients with myelofibrosis previously treated with Jakafi.

An expert explained the importance of education and involvement in care for patients with myeloproliferative neoplasms.

Although Jakafi has been approved for patients with higher-risk myelofibrosis, those with lower-risk disease may also benefit from this treatment.

Vonjo was also shown to improve overall survival in patients with myelofibrosis treated with Vonjo in the real-world setting.

Keri is also a true partner in the management and care of the whole patient.

The Shorespan-007 trial will investigate the new drug among patients with essential thrombocythemia who have not previously received cytoreductive therapy.

Niktimvo was approved for adults and children with chronic, pretreated graft-versus-host disease.

Researchers identified five traits that may increase a person’s chance of experiencing polycythemia vera progression.

The development of new or worsening anemia did not decrease Jakafi’s efficacy in treating primary or secondary myelofibrosis.

I have an incurable cancer, which forces me — and my loved ones — to be ever-adapting in this physical and emotional battle.

Pelabresib plus Jakafi led to a reduction in spleen size and was tolerable in patients with myelofibrosis, according to data from MANIFEST-2.

Childbirth rates have been reduced by 22% in women with MPNs, compared with women without MPNs, researchers found.

Treatment with rusfertide led to a decrease in the need for blood draws and decreased levels of red blood cells in patients with polycythemia vera.

Patients with MPNs who are JAK2V617F- and CALR-positive had different bacterial compositions compared with people without MPNs, research found.

Thomas Silver discusses how a community of support helped a patient when his bone marrow transplant was delayed.

Dr. Douglas Tremblay of the Ichan School of Medicine explains the necessity of cytoreductive therapy for patients with MPNs such as essential thrombocythemia and polycythemia vera.

For patients with myeloproliferative neoplasms, it is essential to have an open relationship with oncology nurses, an expert explained.

Dr. Lucia Masarova sat down with CURE® and discussed the advancements she hopes to see in 2024 for the treatment of patients with myeloproliferative neoplasms.

The three-year final analysis of efficacy and safety of the REACH3 trial showed that patients with steroid-refractory or dependent chronic graft-versus-host disease benefited more with Jakafi compared with the best available treatment.

The recent phase 3 TRANSFORM-1 study concluded that navitoclax combined with Jakafi showed significant spleen volume reductions in patients with myelofibrosis.

CURE® honored eight MPN Heroes, which ranged from medical professionals to patients and caregivers, on the contributions they made in the field.

One expert explained how care team aspects such as open dialogue, support and validation can help to inform patients with MPN about psychosocial needs that tend to be unmet.

Amanda Smith, a registered nurse with Huntsman Cancer Institute, explained the impact early satiety can have on patients with MPNs and why communication with their care team is important.

The FDA approved Ojjaara for intermediate or high-risk myelofibrosis, including primary myelofibrosis or secondary myelofibrosis (post-polycythaemia vera and post-essential thrombocythaemia), in adults with anemia.

Myelofibrosis-related anemia is different than anemia experienced by patients without a cancer diagnosis, a research nurse explained.

Nurse practitioner Charina Toste explains why it is important for patients to be empowered to have educated conversation with their care teams.

Reporting MPN side effects to the care team, regardless of how “little” they may seem, can help determine how to adjust treatment to address these symptoms, an expert said.

We took a look back at the most noteworthy and compelling myeloprolifearative neoplasm stories from 2023.

Patients with MPNs can potentially experience long asymptomatic periods, and it’s up to patients and providers to remain vigilant as they monitor and manage symptoms.