Opinion

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Understanding Prostate-Specific Antigen (PSA) Testing

Key Takeaways

  • Prostate cancer screening is essential for early detection, especially in high-risk groups like men over 50, African Americans, and those with a family history.
  • Routine screening, including PSA tests and digital rectal exams, aids in identifying cancer at an early, treatable stage.
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Panelists discuss how the PSA test is conducted and interpreted, and clarify the definitions of high-risk and advanced prostate cancer types, including their implications for prognosis and subsequent treatment decisions.

Video content above is prompted by the following:

  1. What is a PSA test and how is it performed? How do PSA levels guide next steps? 
  2. Can you explain what high-risk and advanced prostate cancer are, eg, (non-metastatic castration-sensitive prostate cancer (nmCSPC) with BRC at high risk for metastases, castration-resistant prostate cancer (CRPC), and metastatic CSPC (mCSPC)? What is the prognosis for patients diagnosed with advanced disease?

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