Ryan McDonald, Associate Editorial Director for CURE®, has been with the team since February 2020 and has previously covered medical news across several specialties prior to joining MJH Life Sciences. He is a graduate of Temple University, where he studied journalism and minored in political science and history. He considers himself a craft beer snob and would like to open a brewery in the future. During his spare time, he can be found rooting for all major Philadelphia sports teams. Follow Ryan on Twitter @RMcDonald11 or email him at rmcdonald@curetoday.com.
FDA Approves Opdivo-Yervoy Combo for Unresectable Malignant Pleural Mesothelioma
October 2nd 2020The Food and Drug Administration’s approval of Opdivo in combination with Yervoy for patients with unresectable malignant pleural mesothelioma marks the first new systemic therapy approved in more than 15 years in this setting.
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Tecentriq Combo Improves Response Rates in Early TNBC, Regardless of PD-L1 Status
September 22nd 2020Findings from a randomized phase 3 study showed that adding neoadjuvant Tecentriq to a chemotherapy regimen of Abraxane, Adriamycin and Cytoxan in patients with stage 2 or 3 triple-negative breast cancer significantly improved pathologic complete responses, compared with placebo plus chemotherapy.
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Paclitaxel, Carboplatin Regimen Shows Promise in Triple-Negative Breast Cancer
September 17th 2020“This randomized clinical trial found that compared with the conventional anthracycline and docetaxel regimen, the paclitaxel-plus-carboplatin regimen may be an alternative adjuvant chemotherapy strategy for patients with operable TNBC,” the authors wrote.
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Pulling Back the Layers of Penile Cancer
September 17th 2020In this episode of the “CURE Talks Cancer” podcast, we spoke with an expert about some of the possible causes of penile cancer, as well as why research in the field is severely lacking and why it’s so important to inform the public about what to look for in terms of signs and symptoms of this disease.
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Younger Adults, Women with Cancer Respond Less Well to Immunotherapy with Checkpoint Inhibitors
September 16th 2020Younger and female patients with a variety of cancer types tend to have strong immune systems that naturally fight an array of cancer cells. The tumor cells the immune system doesn’t destroy are the most evasive, both to the immune system and medications that boost its activity, and this makes checkpoint inhibitor immunotherapy less effective in this population.
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Cancer Organizations Reflect on Death of Chadwick Boseman, Impact of Young-Onset Colorectal Cancer
September 13th 2020“With education and awareness to defeat the stigma, resources for those diagnosed, and innovative research toward cures, we can end colorectal cancer in our lifetime,” Michael Sapienza, CEO of Colorectal Cancer Alliance, said in a statement.
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The study results also showed that older age was significantly associated with lower cancer genetics knowledge, which, according to a post-doctoral research fellow at Dana-Farber Cancer Institute, is important because older adults may serve as a resource for family members who seek information about their family's health history.
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FDA Warns Tecentriq-Paclitaxel Combination Failed to Treat Locally Advanced or Metastatic TNBC
September 8th 2020The Food and Drug Administration’s warning comes weeks after Genentech, the manufacturer of Tecentriq, issued a press release noting that the IMpassion131 trial failed to meet its primary endpoint of improving progression-free survival in patients with triple-negative breast cancer.
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NIH Issues Grant to Start Studying ‘Chemo Brain’ in Children
September 8th 2020“Our hope is that this will enable us to reduce or eliminate late effects of treatment that persist into the survivorship years,” Dr. Peter Cole, of Rutgers Cancer Institute of New Jersey, said in a press release.
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What’s the Most Surprising Thing That’s Changed Your Life Since Receiving a Cancer Diagnosis?
September 8th 2020On social media, CURE® recently asked its readers to share the most surprising thing that’s changed in their life since receiving a cancer diagnosis. Here, we share some of their responses.
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Cooking with CURE: 5 Summer Recipes Patients with Cancer May Have Missed
September 6th 2020Throughout the summer, CURE® highlighted many simple and healthy recipes that the oncology dietitians from the John Theurer Cancer Center put together for cancer survivors and patients. Here, we share some of those recipes.
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FDA Grants Priority Review to Melflufen-Dexamethasone Combination for Multiple Myeloma
September 4th 2020The Food and Drug Administration granted a priority review to the new drug application for melflufen in combination with dexamethasone for adults with relapsed and refractory multiple myeloma (RRMM) who had previously received multiple lines of therapy.
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“Moving forward, (bendamustine and Rituxan) will likely become a common backbone for the incorporation of other cytotoxic or novel agents in an attempt to further improve outcomes while maintaining an effective, safe, and ideally outpatient regimen for MCL,” the authors wrote.
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FDA Approves Onureg for Continued Treatment of Adults with AML Who Achieved First Complete Remission
September 1st 2020The approval for patients with acute myeloid leukemia was based on data from the phase 3 QUAZAR AML-001 trial, which demonstrated that patients who received Onureg achieved a median overall survival of 24.7 months compared to 14.8 months for those who received placebo.
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Women with Endometrial and Ovarian Cancers Experience Significant Fatigue Following Surgery
August 28th 2020Nearly half (48%) of the patients reported experiencing significant fatigue following their surgery. Thirty-nine percent of the patients still reported significant fatigue one year following their surgery.
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FDA Approves Comprehensive Multi-Tumor Liquid Biopsy Test FoundationOne Liquid CDx for Solid Tumors
August 27th 2020The test was also approved as a companion diagnostic test to determine which select patients with metastatic castration-resistant prostate cancer could benefit from Rubraca, as well as for three frontline TKIs in patients with non-small cell lung cancer.
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