Article

Side Effects Manageable for Newly Approved Folotyn

Author(s):

Vitamin supplementation can reduce certain side effects of Folotyn (pralatrexate), and the majority of patients are able to tolerate the full dose, concluded two safety studies in relapsed or refractory peripheral T-cell lymphoma.

Vitamin supplementation can reduce certain side effects of Folotyn (pralatrexate), and the majority of patients are able to tolerate the full dose, concluded two safety studies in relapsed or refractory peripheral T-cell lymphoma.

One study specifically looked at mucosal inflammation and thrombocytopenia (low platelet counts), two of the most common side effects of the antimetabolite drug Folotyn, and found that it’s appropriate to give patients folic acid and vitamin B12 to minimize these toxic effects.

The second study concluded that two-thirds of patients were able to tolerate the full dose without cumulative side effects. Plus, for patients unable to receive the full dose, reducing their dose by one-third allowed them to continue with therapy.

The Food and Drug Administration approved Folotyn in September, making it the first drug approved in the U.S. for peripheral T-cell lymphoma.

Related Videos
Although late-stage kidney cancer generated poor survival rates for over two decades, significant progress is being made in the treatment of the disease.
There are a number of reasons why patients with cancer are encouraged to enroll in clinical trials, Dr. Michael J. Pishvaian explained.
Use of NeuroSAFE to guide nerve sparing during robot-assisted radical prostatectomy improved patient-reported erectile function.
Adolescent and Young Adult Cancer Awareness Week sheds light on the financial hardships young cancer survivors face, including debt and limited assistance.
CURE spoke with Dr. William C. Huang about what kind of team may be required to treat a patient with metastatic kidney cancer.
Image of woman.
Image of woman.
Image of woman.
Image of woman.
Image of man wearing baseball cap backwards.
Related Content