Article

Age Bias is a Problem for Patients With Breast Cancer

Know your cancer before making a treatment decision.

Breast cancer treatment today is no longer “one size fits all”—what is best for one woman may not be right for another. It’s important to learn as much as possible about your individual breast cancer diagnosis when making a treatment decision. For some patients, a genomic test can help determine whether chemotherapy is necessary in addition to hormone therapy to treat breast cancer and help prevent future recurrences.

Numerous studies, including the landmark TAILORx trial of over 10,000 women using the Oncotype DX® genomic test, demonstrate that the vast majority of women with early-stage, hormone-receptor-positive, HER2-negative breast cancer do not need chemotherapy, according to research from The New England Journal of Medicine. These types of tests have been available for more than a decade, but some breast cancer patients aren’t offered this important tool.

A recent study from the National Cancer Institute’s (NCI) Surveillance, Epidemiology, and End Results (SEER) Registry looked at how often early-stage breast cancer patients were receiving a genomic test to help guide their treatment decisions. With more than 44,600 patients in the SEER study, results revealed that age was a factor influencing whether or not a woman received a genomic test. In fact, genomic testing rates decreased 1.5-fold in younger (under 40) patients and 3-fold in older (over 70) patients when compared to the “typical” age breast cancer patient (ages 40-70), according to researchers.

Traditional assumptions about age, breast cancer aggressiveness, and health may have impacted these patient’s treatment plans — assumptions that all younger breast cancer patients have more aggressive disease and that older breast cancer patients either can’t tolerate or don’t need chemotherapy – resulting in the potential over-treatment or under-treatment of a patient’s breast cancer. It is important to recognize that not all cancers are the same.

No Matter My Age was created to help educate and raise awareness about the need for all breast cancer patients — regardless of their age – to get as much information as they can before making a treatment decision.

This means learning how to self-advocate and to ask questions about care options, including whether a genomic test may help determine the best treatment plan. To learn more, visit No Matter My Age.

Related Videos
Dr. Debu Tripathy discussed the importance of understanding the distinctions between HER2-low and HER2-ultralow breast cancer.
Dr. Debu Tripathy is a professor and chairman of the Department of Breast Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, in Houston, and the editor-in-chief of CURE®.
Dr. Azka Ali is a medical oncologist at the Cleveland Clinic Taussig Cancer Institute, in Ohio.
Dr. Maxwell Lloyd, a Clinical Fellow in Medicine in the Department of Medicine at Beth Israel Deaconess Medical Center in Boston.
Dr. Maxwell Lloyd, a Clinical Fellow in Medicine, in the Department of Medicine, at Beth Israel Deaconess Medical Center in Boston.
Dr. Aditya Bardia is a professor in the Department of Medicine, Division of Hematology/Oncology, director of Translational Research Integration, and a member Signal Transduction and Therapeutics, at University of California, Los Angeles (UCLA) Health Jonsson Comprehensive Cancer Center.
Image of a woman with light shoulder-length hair, wearing rectangular glasses.
Image of man with grey hair.
Image of woman with blonde hair.