Navigating Polycythemia Vera (PV): Symptom Recognition and Management

A panelist discusses how polycythemia vera (PV) is a rare myeloproliferative neoplasm (MPN) characterized by excessive red blood cell production, primarily affecting older adults with JAK2 mutations, and while it can be managed with treatment, patients face increased risks of blood clots and potential progression to more serious conditions.

A panelist discusses how polycythemia vera (PV) symptoms can vary significantly among patients, but commonly include headaches, dizziness, itching (especially after warm baths), fatigue and visual disturbances, with some patients experiencing more severe manifestations like blood clots while others may be relatively asymptomatic.

A panelist discusses how patients with polycythemia vera (PV) often present with diverse symptoms ranging from fatigue and itching to cardiovascular complications, leading doctors to conduct specific diagnostic tests including complete blood counts, JAK2 mutation analysis and bone marrow biopsies, although diagnosis can be challenging due to symptom overlap with other conditions and varying presentation patterns.

panelist discusses how polycythemia vera (PV) treatment approaches include both therapeutic phlebotomy and medications like hydroxyurea or interferon to control blood counts, with treatment selection based on individual risk factors and symptoms, while patients can actively participate in their care through lifestyle modifications and regular monitoring of blood counts, symptoms and cardiovascular risk factors to achieve both immediate symptom relief and long-term disease control.