CURE’s colorectal cancer page is an extensive resource of cancer information featuring the latest colorectal cancer news, expert oncologist insights on the latest cancer treatments, oncology research, advocacy efforts, and medical data on colorectal cancer.
March 28th 2025
Favorable initial results from a phase 1/2 trial of solnerstotug in PD-L1–resistant tumors showed a 14% response rate and 62% disease control rate.
Immunotherapy Combination Shows Promise, Side Effects Ensue in Colorectal Cancer Subgroup
May 25th 2018Despite improved outcomes, the researchers also found that side effects with checkpoint inhibition often affected the dermatologic, gastrointestinal, pulmonary, renal, endocrine and hepatic systems in patients.
Genetic Testing Is Important for Both Patients and Family Members
March 19th 2018The understanding of genetic mutations, like tumors that are microsatellite instability-high (MSI-H), and the therapies that go along with them is transforming the world of colorectal cancer, according to John Marshall, M.D.
Exploring Clonal Evolution in Colorectal Cancer
January 27th 2018Patients with microsatellite instability-high (MSI-H) colorectal cancer may undergo a distinct pattern of clonal evolution, which in turn, would impact the use of targeted and immunologic therapies in these patients, according to study results presented at the 2018 Gastrointestinal Cancer Symposium.
Molecular Testing Is Key in Understanding MSI-H Colorectal Cancer
January 16th 2018In recent years, next-generation sequencing has allowed physicians and researchers alike to gather more genetic data for patients with gastrointestinal cancers. And while this kind of profiling continues to advance, so do treatment options for this patient population.
Examining Response Rates in MSI-H and NTRK Fusion GI Cancers
January 11th 2018Luis A. Diaz, M.D., head of the division of Solid Tumors at Memorial Sloan Kettering Cancer Center, discusses response rates in patients with microsatellite instability-high (MSI-H) or NTRK fusion gastrointestinal (GI) cancers.