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November 2007
More CT scans mean higher radiation exposure
November 28, 2007
NEW YORK (Reuters Health) - US researchers argue that the growth in the number of CT scans performed over the years has increased the likelihood of higher radiation exposures, which may result in a significant public health problem.
Freezing tumors eases cancer pain in study
November 28, 2007
CHICAGO (Reuters) - Freezing tumors may help relieve the extreme pain of cancer that has spread to the bone, which is often untouched by narcotics or radiation, U.S. researchers said on Tuesday.
Breast cancer pain more severe in non-whites
November 26, 2007
NEW YORK (Reuters Health) - Results of a study show significant racial differences in the risk of pain associated with advanced breast cancer, with non-whites experiencing poorer pain control than women of other races.
Nutritional status impacts treatment response, survival in esophageal cancer
November 23, 2007
NEW YORK (Reuters Health) - In patients with locally advanced esophageal cancer, poor baseline nutritional status is associated with nonresponse to definitive chemoradiotherapy and shorter survival, independent of clinical and tumor characteristics, according to a retrospective study.
Drug boosts survival of relapsed multiple myeloma
November 22, 2007
NEW YORK (Reuters Health) - Adding the drug lenalidomide, a less-toxic relative of the drug thalidomide, to standard dexamethasone therapy can improve survival in patients with relapsed or hard-to-treat multiple myeloma -- a cancer of the blood.
Post-therapy PET imaging predicts outcome in cervical cancer
November 21, 2007
NEW YORK (Reuters Health) - Positron emission tomography (PET) using F-18 fluorodeoxyglucose (FDG) performed 3 months after treatment for cervical cancer is helpful in determining response to treatment and predicting outcome, a study shows. Simplified model predicts estrogen receptor-positive breast cancer risk
November 21, 2007
NEW YORK (Reuters Health) - A simplified model that includes age, breast cancer in first-degree relatives, and previous breast biopsy examination identifies women at risk for estrogen receptor (ER)-positive (but not ER-negative) breast cancers, according to a report in the November 21st Journal of the National Cancer Institute. CT colonography often detects extracolonic abnormalities in older patients
November 20, 2007
NEW YORK (Reuters Health) - Two thirds of elderly patients undergoing CT colonography (CTC) for lower gastrointestinal symptoms will have one or more extracolonic abnormalities detected, which, in many cases, are clinically significant, new research shows. PSA levels lower in obese men due to hemodilution
November 20, 2007
NEW YORK (Reuters Health) - Hemodilution related to larger plasma volume may be responsible for the lower prostate-specific antigen (PSA) levels observed in overweight and obese men as compared with normal weight men, new findings suggest.
Resistance temozolomide in leukemia tied to DNA repair activity
November 20, 2007
NEW YORK (Reuters Health) - In pediatric patients with refractory or recurrent leukemia, temozolomide resistance is associated with activity of the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT), researchers report in the November 1st issue of the Journal of Clinical Oncology. Most cases of T-cell precursor ALL appear to develop after birth
November 20, 2007
NEW YORK (Reuters Health) - A retrospective study of children diagnosed with T-cell precursor acute lymphoblastic leukemia (TCP ALL) concludes, based on PCR studies of stored neonatal blood spots, that most cases of the disease develop after birth, not in utero.
Obesity raises prostate cancer death risk
November 19, 2007
NEW YORK (Reuters Health) - Men who are overweight or obese at the time they are diagnosed with prostate cancer are nearly twice as likely to die from their disease after treatment as men who are not overweight or obese.
Nexavar becomes first drug approved for liver cancer
November 19, 2007
The Food and Drug Administration added liver cancer to the approved indications of Nexavar (sorafenib), an oral targeted therapy initially approved for kidney cancer. The approval made Nexavar the first systemic drug therapy for unresectable hepatocellular carcinoma (HCC), and the only drug therapy shown to significantly improve overall survival in patients with the disease.
Patients with small cell carcinoma of the prostate have a poor outcome
November 16, 2007
NEW YORK (Reuters Health) - The prognostic outcome is poor in patients with small cell carcinoma of the prostate, according to results of a study published in the October 15th issue of Cancer. Serum lactate dehydrogenase (LDH) and albumin levels at the time of diagnosis may be predictive of disease-related outcomes.
Tamoxifen superior to arzoxifene for locally advanced or metastatic breast cancer
November 16, 2007
NEW YORK (Reuters Health) - Compared with arzoxifene, tamoxifen provides longer progression-free survival and time to treatment failure in women with locally advanced and metastatic breast cancer, according to a report in the November 1st Journal of Clinical Oncology.
Obesity may explain rising rate of esophageal and gastric cardia adenocarcinoma
November 15, 2007
NEW YORK (Reuters Health) - Increasing body mass index (BMI) is associated with an increased risk of esophageal and gastric cardia adenocarcinoma, and may account for the rising incidence of these diseases, researchers report.
Picornavirus promising against metastatic cancer
November 15, 2007
NEW YORK (Reuters Health) - The newly discovered native picornavirus Seneca Valley Virus-001 shows powerful and selective cytolytic action in tumor cell lines, researchers report in the November 7th issue of the Journal of the National Cancer Institute.
Dasatinib therapy for leukemia may lead to lung problems
November 14, 2007
NEW YORK (Reuters Health) - Lung abnormalities are seen in a significant minority of patients after dasatinib treatment for chronic myeloid leukemia, according to a case series compiled by French investigators.
Menopausal symptoms vary with tamoxifen or exemestane for breast cancer
November 14, 2007
NEW YORK (Reuters Health) - Among postmenopausal women receiving adjuvant therapy for early breast cancer women, exemestane is associated with fewer hot flashes than is tamoxifen but with more difficulty sleeping, according to a study published in the October 20th issue of the Journal of Clinical Oncology.
Electromagnetic anisotropy detects prostate cancer noninvasively
November 14, 2007
NEW YORK (Reuters Health) - The tissue-resonance interaction method (TRIM) for analyzing electromagnetic anisotropy can be used to detect prostate cancer noninvasively, according to a report in the November issue of BJU International.
Bevacizumab plus irinotecan prolongs survival in recurrent glioblastoma
November 7, 2007
NEW YORK (Reuters Health) - Phase II trial results show that dual treatment with irinotecan and bevacizumab prolongs survival in cases of recurrent glioblastoma multiforme. Early invasive cervical cancer imaging better with MRI than CT
November 7, 2007
NEW YORK (Reuters Health) - MRI is better than CT for preoperative evaluation of early invasive cervical cancer, but both modalities are less than perfect, according to a report in the November issue of Radiology. Osteopontin expression predicts colon cancer survival
November 7, 2007
NEW YORK (Reuters Health) - Levels of osteopontin, a highly overexpressed protein in several types of solid tumors, are predictive of survival in patients with colon cancer, German researchers report.
U.S. voters OK bonds for cancer research, highways
November 7, 2007
NEW YORK (Reuters) - Texas voters approved all statewide bond measures on Tuesday's ballot, including $3 billion for a state cancer institute, but New Jersey rejected borrowing $450 million for stem cell research, initial election results showed on Wednesday.
HPV vaccine Gardasil protects older women
November 5, 2007
CHICAGO (Reuters) - Gardasil, Merck's HPV vaccine for preventing cervical cancer in girls and women aged 9 to 26, may offer protection for women up to age 45, the company said on Sunday.
Exercise, counseling fights cancer-related fatigue
November 2, 2007
NEW YORK (Reuters Health) - Both exercise therapy and psychological counseling might offer some relief from the fatigue that often plagues cancer patients, a new research review suggests.
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